Paediatric Dermatology Column: Case Report Silvery hair syndromes: report of familial cases of Griscelli syndrome in three siblings

Silvery hair is a rare clinical feature, common in a group of rare syndromes, which usually present in the paediatric age group termed together as "silvery hair syndromes". We report a consanguineous family in which three out of four siblings had silvery hair and neurological deficits and were diagnosed to have Griscelli syndrome. The diagnosis of Griscelli syndrome in our cases was based on clinical findings with severe neurological impairment in the absence of immunodeficiency and the characteristic findings of hair light microscopy.